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Apoptosis and Beyond: The Many Ways Cells Die, 2-Volume Set, 1st Edition |
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¡¡These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death
¡¡This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each.
¡¡Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death.
¡¡¤ýCovers all known processes that dying cells undergo
¡¡¤ýProvides extensive coverage of a topic not fully covered before
¡¡¤ýOffers chapters written by top researchers in the field
¡¡¤ýProvides activities that link and contrast processes to each other
¡¡Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.
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List of Contributors ix
Volume 1
1 General View of the Cytoplasmic and Nuclear Features of Apoptosis 1
2 Mitochondria in Focus: Targeting the Cell-Death Mechanism 13
3 Microbial Programmed Cell Death 49
4 Autophagy 71
5 Cell Injury, Adaptation, and Necrosis 83
6 Necroptosis 99
7 Ferroptosis 127
8 Anoikis Regulation: Complexities, Distinctions, and Cell Differentiation 145
9 Cornification 183
10 Excitotoxicity 197
11 Molecular Mechanisms Regulating Wallerian Degeneration 205
12 Pyronecrosis 225
13 Phenoptosis: Programmed Death of an Organism 237
14 Molecular Mechanisms Underlying Oxytosis 289
15 Pyroptosis 317
16 Paraptosis 343
17 Hematopoiesis and Eryptosis 367
Volume 2
18 Cyclophilin D-Dependent Necrosis 375
19 Role of Phospholipases in Cell Death 395
20 TRIAD (Transcriptional Repression-Induced Atypical Death) 411
21 Alkylating-Agent Cytotoxicity Associated with O6-Methylguanine 427
22 Entosis 463
23 Mitotic Catastrophe 475
24 NETosis and ETosis: Incompletely Understood Types of Granulocyte Death and their Proposed Adaptive Benefits and Costs 511
25 Parthanatos: Poly ADP Ribose Polymerase (PARP)-Mediated Cell Death 535
26 Methuosis: Drinking to Death 559
27 Oncosis 567
28 Autoschizis: A Mode of Cell Death of Cancer Cells Induced by a Prooxidant Treatment In Vitro and In Vivo 583
29 Programmed Death 1 (PD1)-Mediated T-Cell Apoptosis and Cancer Immunotherapy 695 |
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