From Book News, Inc.
Researchers in microbiology, pathology, allergy and immunology, and biomedical science review the activation of the mammalian immune system by bacterial DNA and consider the application of immunostimulatory DNA sequences (ISS) in clinical medicine. They survey the latest findings on the receptor-recognition and signaling pathways triggered by ISS, the process of cell activation, and potential vaccination strategies using ISS. Specific pharmaceutical applications discussed include infectious diseases, allergy, cancer, and inflammation and autoimmunity. The book is of interest to immunologists, bacteriologists, pharmacists, allergists, and infectious disease specialists. Raz is affiliated with the University of California-San Diego.Book News, Inc., Portland, OR

Book Info
Univ. of California, San Diego at La Jolla. Text explains the immunobiology of bacterial DNA and its promise of powerful new vaccines to provide protective immunity against infections, tumors, and diseases. Features current reviews of immune activation, vaccine applications, vaccination strategies, TLR signaling pathway, and its microbial ligands.DNLM: Bacterial--immunology.