Editorial Reviews From Book News, Inc. Neurological specialists from around the world report on clinical evidence that immunophilins and structurally similar ligands given to patients who have received organ or neural transplants, possess neurotrophic and neuroprotective properties in addition to their immuno-suppressive effects, and thus may promote graft survival and function as well as inhibiting graft rejection. Citing research on animals with neurological disorders, they discuss immuno-suppressants and Parkinson's Disease, other age- related diseases, stroke, traumatic brain injury, spinal cord injury, sciatic nerve injury, and other disorders of the central nervous system.Copyright 2004 Book News, Inc., Portland, OR
Book Info The third author, Paul R. Sandberg, is with the Univ. of Southern Florida, Tampa. Text demonstrates the exertion of immunophilins' neuroprotective effects as a new breed for the treatment of neurological disorders. Includes laboratory studies and hypotheses. Electronic format not available. DNLM: Immunosuppressive Agents--therapeutic use.
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