Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management.

New seventh edition highlights:
* Review questions and answers in each chapter prepare students for course and board exams.
* New contributors include cardiology fellows and internal medicine residents, who worked closely with faculty to extend coverage of clinically pertinent issues for medical students.
* Updated content reflects the latest understanding of mechanisms of cardiac disease and technological advances.

Classic student-friendly features:
* Full-color illustrations help readers visualize and quickly grasp key concepts.
* Medical imaging and color clinical photographs show real-world examples of many clinically relevant cardiovascular conditions.
* Introductory chapter outlines and end-of-chapter summaries provide organized, quick review of core information.

Bonus online study tools:
* Animations help support understanding of complex, dynamic disease processes.
* Interactive question bank reinforces learning and improves retention.

xi
Table of Contents
List of Contributors vi
Foreword viii
Preface ix
CHAPTER 1
Normal Cardiac Structure and Function 1
Ershela Durresi, Elazer R. Edelman,
and Leonard S. Lilly
CHAPTER 2
The Cardiac Cycle: Mechanisms of Heart
Sounds and Murmurs 28
Vivek T. Kulkarni and Leonard S. Lilly
CHAPTER 3
Cardiac Imaging and Hemodynamic
Assessment 46
Sanjay Divakaran and Ron Blankstein
CHAPTER 4
The Electrocardiogram 79
Daniel C. Pipilas, Bruce A. Koplan,
and Leonard S. Lilly
CHAPTER 5
Atherosclerosis 118
Siddharth M. Patel and Peter Libby
CHAPTER 6
Ischemic Heart Disease 142
David D. Berg, Marc S. Sabatine, and Leonard S. Lilly
CHAPTER 7
Acute Coronary Syndromes 172
David D. Berg, Marc S. Sabatine, and Leonard S. Lilly
CHAPTER 8
Valvular Heart Disease 202
Diana M. Lopez, Patrick T. O’Gara,
and Leonard S. Lilly
CHAPTER 9
Heart Failure 232
Lauren A. Eberly, Eldrin F. Lewis, and Leonard S. Lilly
CHAPTER 10
The Cardiomyopathies 265
Lauren A. Eberly, Neal K. Lakdawala,
and Leonard S. Lilly
CHAPTER 11
Mechanisms of Cardiac Arrhythmias 285
Victor Nauffal and Leonard S. Lilly
CHAPTER 12
Clinical Aspects of Cardiac
Arrhythmias 305
Victor Nauffal and Leonard S. Lilly
CHAPTER 13
Hypertension 330
Jenifer M. Brown, Gordon H. Williams,
and Leonard S. Lillyxii Table of Contents
CHAPTER 14
Diseases of the Pericardium 355
Mathew S. Lopes and Leonard S. Lilly
CHAPTER 15
Diseases of the Peripheral
Vasculature 373
Stanislav Henkin and Mark A. Creager
CHAPTER 16
Congenital Heart Disease 398
Jonathan W. Cunningham and David W. Brown
CHAPTER 17
Cardiovascular Drugs 427
Ankeet S. Bhatt, Victor Nauffal, and Leonard S. Lilly
Index 487