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The Peripheral T-Cell Lymphomas,1e |
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Peripheral T-cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represents 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat.
The first book of its kind, The Peripheral T-Cell Lymphomas presents a far-reaching survey of this complex and rare group of blood cancers. Featuring contributions from thought-leaders concerned with all aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource:
* Covers the biological basis, epidemiology, classification, and treatment of PTCL
* Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL
* Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation
* Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations
* Features contributions from the Chairs The T-Cell Lymphoma Forum: the world¡¯s largest meeting focused on PTCL
Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly those working in oncology and hematology.
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Part 1: Biological Basis of the Peripheral T-Cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡1 Fundamentals T-Cell Lymphocyte Biology
¡¡¡¡¡¡¡¡-¡¡2 Mechanisms of T-cell Lymphomagenesis
¡¡¡¡¡¡¡¡-¡¡3 Epigenetics of T-cell Lymphoma
¡¡¡¡¡¡¡¡-¡¡4 Animal Models of T-cell Lymphoma
Part 2: Epidemiology and Classification of the PTCL
¡¡¡¡¡¡¡¡-¡¡5 The Geographic Distribution of the PTCL: Global Epidemiology
¡¡¡¡¡¡¡¡-¡¡6 Classification of the Peripheral T-Cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡7 Molecular Classification of the PTCLs
Part 3: Discrete Clinical Subtypes of PTCL (Unique Epidemiology, Therapy and Management)
¡¡¡¡¡¡¡¡-¡¡8 Peripheral T-Cell Lymphoma ¦¡ Not Otherwise Specified
¡¡¡¡¡¡¡¡-¡¡9 Angioimmunoblastic T-cell Lymphoma (AITL)
¡¡¡¡¡¡¡¡-¡¡10 The Spectrum of Anaplastic Large Cell Lymphoma
¡¡¡¡¡¡¡¡-¡¡11 HTLV-1-Positive Adult T-Cell Leukemia-Lymphoma (ATL)
¡¡¡¡¡¡¡¡-¡¡12 Natural Killer/T Cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡13 T-Prolymphocytic Leukemia (T-PLL)
¡¡¡¡¡¡¡¡-¡¡14 Large Granular Lymphocytes Leukemia (LGL)
¡¡¡¡¡¡¡¡-¡¡15 Gamma Delta T-cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡16 Enteropathy Associated T-Cell Lymphoma and Monomorphic Epitheliotropic Intestinal T-cell lymphoma
¡¡¡¡¡¡¡¡-¡¡17 Hepatosplenic T-Cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡18 Cutaneous T-Cell Lymphoma
¡¡¡¡¡¡¡¡-¡¡19 Other Rare Subtypes of PTCL
Part 4: Treatment of the PTCL
¡¡¡¡¡¡¡¡-¡¡20 Standard Front-line Therapies
¡¡¡¡¡¡¡¡-¡¡21 Approved Agents in the Relapsed or Refractory Setting, Excluding Brentuximab vedotin
¡¡¡¡¡¡¡¡-¡¡22 The Role for Autologous Stem Cell Transplantation (ASCT) in Peripheral T Cell Lymphomas (PTCL)
¡¡¡¡¡¡¡¡-¡¡23 Allogeneic Stem Cell Transplantion
¡¡¡¡¡¡¡¡-¡¡24 Emerging Immunotherapy Approaches in Peripheral T-Cell Lymphomas
¡¡¡¡¡¡¡¡-¡¡25 Emerging New Small Molecules in Peripheral T-Cell Lymphomas
Part 5: Future Directions
¡¡¡¡¡¡¡¡-¡¡26 The Value and Relevance of T-cell Lymphoma Registries
¡¡¡¡¡¡¡¡-¡¡27 Innovative Chemotherapy-Free Approaches for the Treatment of PTCL
¡¡¡¡¡¡¡¡-¡¡28 Global Collaborations |
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