From Book News, Inc.
Three dozen chapters contribute to researchers' understanding of the molecular mechanisms involved in the breakdown of the blood-brain barrier (BBB) in brain disorders caused by stroke, trauma, inflammation, and tumors. In sections on tissue and permeability techniques, Nag (neuropathology, U. of Toronto) introduces the properties of cellular components of normal cerebral vessels and the pathophysiology of BBB breakdown. Other contributors provide step-by- step instructions on BBB transport, in vitro, molecular, and genomic methods, and discuss genetically altered models.Copyright 2004 Book News, Inc., Portland, OR

Book Info
Univ. of Toronto, Canada. Text provides the details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies. Each part is preceded by a review emphasizing the advantages and pitfalls of particular techniques. Written for researchers in BBB. DNLM: Blood--Brain Barrier--physiology.