Description

For courses in Molecular Biology, Molecular Genetics, and Gene Regulation.

Two decades ago Benjamin Lewin's Genes revolutionized the teaching of molecular biology and molecular genetics by introducing a unified approach to bacteria and higher organisms. Genes has remained at the cutting edge of molecular biology, covering gene structure, organization, and expression.

Originally the text opened with the genetic code and worked toward genome structure. Genes VIII changed the approach to begin with the sequence of the human and other genomes and starts with complete coverage of recent advances in genomics. The coverage of genomics is then integrated throughout the text.
In striving to maintain currency, the new edition has updated coverage on genome organization, DNA replication, gene regulation and many other new topics.

Features

NEW - Integration of Genomics_Approach now begins with sequencing of human and other genomes allowing for complete integration of advances in genomics throughout the text.
Provides a more current and cutting edge introduction to molecular biology.

NEW - Added and revised content throughout_New or revised topics include: genome organization, DNA replication, repair, and recombination, transcription and translation, as well as recent advances in cancer and signal transduction.

NEW - Unique website provides for continual updates_(www.prenhall.com/lewin) Includes an E-book enhanced with weekly updates and flash illustrations.
Weekly electronic updates keep professors and students continually apprised of the latest developments in the field.

Hyperlinks provide access to the original research wherever possible.

Multiple views allow professors or students to view the online material in the way that is best suited to their teaching/learning style, from straight text to visual slides or a combination of both.

Unified approach _First book to take a unified approach to bacteria and higher organisms.
Allows for a comparison of similar structure and function among prokaryotes and eukaryotes.

Extensive illustrations.
Enhances and clarifies every conceptual point, from simple introductions to more complex conclusions

(NOTE: Every chapter opens with an Introduction and concludes with a Summary.)

I. GENES.
1. Genes are DNA.
2. The Interrupted Gene.
3. The Content of the Genome.
4. Clusters and Repeats.

II. PROTEINS.
5. Messenger RNA.
6. Protein Synthesis.
7. Using the Genetic Code.
8. Protein Localization.

III. GENE EXPRESSION.
9. Transcription.
10. The Operon.
11. Regulatory Circuits.
12. Phage Strategies.

IV. DNA.
13. The Replicon.
14. DNA Replication.
15. Recombination and Repair.
16. Transposons.
17. Retroviruses and Retroposons.
18. Rearrangement of DNA.

V. THE NUCLEUS.
19. Chromosomes.
20. Nucleosomes.
21. Promoters and Enhancers.
22. Activating Transcription.
23. Controlling Chromatin Structure.
24. RNA Splicing and Processing.
25. Catalytic RNA.
26. Immune Diversity.

VI. CELLS.
27. Protein Trafficking.
28. Signal Transduction.
29. Cell Cycle and Growth Regulation.
30. Oncogenes and Cancer.
31. Gradients, Cascades, and Signaling Pathways.

Glossary.

Index.