Key Features


•Reviews common medical cardiac complications of prevalent rheumatologic inflammatory and autoimmune diseases
•Addresses aspects of pathophysiological processes, clinical presentations, prognostic implications, and novel therapeutic approaches
•Presents an up-to-date level of evidence and strengths of recommendations for suggested therapies, and reviews all randomized clinical trials, meta-analyses, and other supporting published clinical findings
•Divides chapters into a unique substructure, simplifying the presentation of this complex subject area


Description



The Heart in Rheumatologic, Inflammatory and Autoimmune Diseases: Pathophysiology, Clinical Aspects and Therapeutic Approaches examines the complex mechanisms related to cardiac diseases in rheumatologic autoimmune and inflammatory conditions from a pathophysiological and clinical point-of-view.

It is known that some rheumatologic diseases are associated with a higher risk of cardiac involvements that can have major influences on clinical outcomes, quality of life, and overall prognosis. Also, systemic inflammatory conditions and autoimmune processes may affect the heart. Surprisingly, many rheumatologists and cardiologists are unaware of cardiac involvement in rheumatologic and inflammatory diseases.

This important reference brings together an understanding of the molecular and cellular processes and natural history of cardiac abnormalities in rheumatologic and inflammatory diseases, making this essential reading for improving patient care and forwarding research in this area. In addition, a broad review of novel therapeutic approaches with special attention to the cardiovascular aspects of treatments for rheumatologic and inflammatory conditions will provide the caregiver with a valuable reference.


Readership

Researchers of cardiology, cardiologists, resident and medical students as well as clinical rheumatologists and rheumatologists involved in clinical research

1: Pathophysiology and Molecular Basis of Autoimmune and Inflammatory Diseases

2: Organ-specific autoimmune myocardial diseases: from pathogenesis to diagnosis and management

3: Autoantibodies against G-protein coupled receptors in cardiovascular diseases: basics and diagnosis

4: Immune mediated accelerated atherosclerosis

5: A study of cardiac function, atherosclerosis and arrhythmogenicity

6: Rheumatoid arthritis

7: Juvenile idiopathic arthritis

8: Spondyloarthritis: ankylosing spondylitis, reactive arthritis, and psoriatic arthritis

9: Polymyalgia rheumatica

10: Systemic lupus erythematosus

11: Neonatal lupus

12: Sjögren’s Syndrome and maternal Sjögren syndrome

13: Systemic sclerosis

14: Dermatomyositis and polymyositis

15: Gout

16: Giant cell arteritis

17: Takayasu's arteritis

18: Polyarteritis nodosa

19: Kawasaki disease

20: ANCA-associated vasculitides (microscopic polyangiitis, Churg-Strauss syndrome and Wegener's granulomatosis)

21: Behçet's disease

22: Rheumatic fever

23: Chagas cardiomyopathy

24: Familial Mediterranean fever

25: Desirable and adverse effect of anti-inflammatory agents on the heart

26: Immunosuppressive cytotoxic drugs

27: Autoantibody directed therapy in cardiovascular diseases

28: Cardiac Immunomodulation