From Book News, Inc.
Overviews the theoretical principles and practical methods underlying the DOE Human Genome Project and modern molecular genetics and biotechnology. The book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. Cantor and Smith (biomedical engineering, Boston University) then describe the three main techniques used in DNA analysis<-->hybridization, polymerase chain reaction, and electrophoresis<-->and explore DNA mapping in its many different forms. For chemists, biologists, computer scientists, engineers, and physicians. Book News, Inc.?, Portland, OR

Human Genetics, May 2000
"this book is to be highly recommended..."

DNA Chemistry and Biology.

A Genome Overview at the Level of Chromosomes.

Analysis of DNA Sequences by Hybridization.

Polymerase Chain Reaction and Other Methods for In Vitro DNA Amplification.

Principles of DNA Electrophoresis.

Genetic Analysis.

Cytogenetics and Pseudogenetics.

Physical Mapping.

Enhanced Methods for Physical Mapping.

DNA Sequencing: Current Tactics.

Strategies for Large-Scale DNA Sequencing.

Future DNA Sequencing Without Length Fractionation.

Finding Genes and Mutations.

Sequence-Specific Manipulation of DNA.

Results and Implications of Large-Scale DNA Sequencing.

Appendix.

Index.