Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. This new edition features access to the fully searchable text online at www.expertconsult.com, where you'll find a downloadable image gallery and exclusive web-only content for added value.
* Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders.

* Choose treatment protocols based on the best scientific evidence available today.

* Apply the knowledge and experience of the leading experts in the field.

New and updated content on the latest diagnostic perspectives and approaches to therapy.

3 brand new chapters: Laboratory Investigations, CNA Vasculitis, Other Vasculitis

Expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies.

The globalization of the specialty of pediatric rheumatology is recognized by the inclusion of information about diagnosis and management of childhood rheumatic diseases in the southern hemisphere

The new, full-color edition of Cassidy helps you to overcome the challenges of pediatric rheumatology with comprehensive coverage of the latest advances in this constantly evolving field.

Section 1: Basic Concepts and Fundamentals

1. Pediatric Rheumatology: the Study of Rheumatic Diseases in Childhood and Adolescence

2. Structure and Function

3. Immunology: Building Blocks

4. Immunology: Translation

5. Integrative Genomics


Evaluation

6. TRIAL DESIGN, MEASUREMENT, AND ANALYSIS OF CLINICAL INVESTIGATIONS

7. Assessment of Health Status

8. Pain and its Assessment

9. Radiology

10. Laboratory Investigations


Management

11. Managing Children with Rheumatic Diseases

12. Pharmacology Non-Biologics

13. Pharmacology Biologics

14. Occupational and Physical Therapy for Rheumatic Diseases


Section 2: Chronic Arthritis

15. Chronic Arthritis in Children and Adolescence

16. Systemic Juvenile Idiopathic Arthritis

17. POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

18. OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS

19. Enthesitis Related Arthritis

20. Juvenile Psoriatic Arthritis

21. Arthropathies of Inflammatory Bowel Disease

22. UVEITIS IN JUVENILE IDIOPATHIC ARTHRITIS


Section 3: Systemic Connective Tissue Diseases

23. Systemic Lupus Erythematosus

24. Antiphospholipid Syndrome

25. Neonatal Lupus

26. Juvenile Dermatomyositis

27. Systemic Sclerodermas

28. Localized Sclerodermas

29. MIXED CONNECTIVE TISSUE DISEASE AND UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE

30. Sjogren's Syndrome

31. Raynaud Phenomenon


Section 4: Vasculitis

32. Vasculitis And Its Classification

33. Leukocytoclastic Vasculitis: Henoch-Schönlein Purpura, and Hypersensitivity Vasculitis

34. POLYARTERITIS NODOSA

35. Kawasaki Disease

36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis

37. CNS Vasculitis

38. Other Vasculitis

39. PEDIATRIC SARCOIDOSIS

40. Behcet Disease


Section 5: Arthritis Related to Infection

41. Infectious Arthritis and Osteomyelitis

42. Lyme Disease

43. Reactive Arthritis

44. Rheumatic Fever

45. Musculoskeletal Manifestations of Systemic Disease

46. Immunodeficiencies

47. Systemic Autoinflammatory Diseases

48. Autoinflammatory Bone Disorders

49. Macrophage Activation Syndrome

50. Malignancies


Section 6: Noninflammatory Musculoskeletal Pain

51. Noninflammatory Musculoskeletal Pain

52. Pain Amplification Syndromes

53. Disorders of Bone Mineralization

54. Primary Disorders of Connective Tissue