From Book News, Inc.
Presenting information in an accessible layout, with brief chapters and many bulleted points, this work reviews the pathophysiologic basis of selected diseases and provides a rationale for drug therapies. Chapters are organized by disease state affecting each organ system, with descriptions of conditions and detailed rationales for therapy and treatment, plus study objectives, key terms, and boxes providing concise synopses of generic and class names, routes of administration, and major side effects of selected drugs. The book stresses topics in pathophysiology that are most pertinent to students pursuing degrees in pharmacy.Book News, Inc., Portland, OR

Book Description
Presenting all the information your students need in an accessible layout, Essentials of Pathophysiology for Pharmacy will give students a practical understanding of the pathophysiologic basis of selected diseases while providing a rationale for subsequent drug therapy.

Book Info
Provides a concise learning instrument for the understanding of the pathophysiologic basis of selected diseases while providing a rationale for subsequent drug therapy. Features organization by disease, study objectives, drug therapies to be applied to the clinical applications, and key term boxes. DNLM: Pathology--methods.

CELLULAR INJURY
Cellular adaptation
Mechanism of cellular injury
Classification of cellular injury
Manifestations of cellular injury
Cell death
Types of cellular necrosis
Tissue repair mechanisms
Steps in wound healing
Factors that impair wound healing

CANCER
Estimated number of new cancer cases
Cancer terminology
Characteristics of neoplasia
Theories of oncogenesis
Cancer causing agents
Manifestations of cancer
Tumor staging
Cancer detection
Tumor markers
Treatment of cancer

DISORDERS OF HEMOSTASIS AND COAGULATION
Steps in hemostasis
Coagulation pathways
Conditions leading to decreased coagulation
Anticoagulant drugs
Conditions leading to increased coagulation

ALTERATIONS IN HEMATOLOGIC FUNCTION AND OXYGEN TRANSPORT
Hematopoiesis
Analysis of blood cells
Anemia
Sickle cell disease
Thalassemia
Polycythemia

IMMUNE RESPONSE AND INFLAMMATION
Components of the immune system
Immune cell function
Antibody structure and function
Cytokine actions
The inflammatory reaction
Hypersensitivity reactions
Anaphylaxis

ACQUIRED IMMUNE DEFICIENCY SYNDROME
HIV structure
Stages of HIV infection
Opportunistic infections in AIDS
Epidemiology of HIV infection
Laboratory diagnosis of HIV
HIV treatment and prevention
HIV drug resistance

DISEASES OF VASCULAR SYSTEM
Arterial diseases
Atherosclerosis, lipoproteins
Genetic disorders of lipid metabolism
Aneurysm
Vasospastic conditions
Arterial inflammation
Diseases of the veins
Varicose veins
Chronic venous insufficiency
Venous thrombus
Embolism
Anticoagulant and Thrombolytic drug therapy

ALTERATIONS IN BLOOD PRESSURE
Primary or essential hypertension
Blood pressure measures
Risk factors for hypertension
Manifestations of essential hypertension
Treatment of hypertension
Secondary hypertension
Malignant hypertension
Hypotension
Causes of orthostatic hypotension


DISEASES OF THE HEART
Diseases of the pericardium
Diseases of the myocardium
Diseases of the endocardium and heart valves
Congenital heart defects

MYOCARDIAL ISCHEMIA
Myocardial oxygen balance
Manifestations of myocardial ischemia, types of angina pectoris
Diagnosis of myocardial ischemia
Treatment of myocardial ischemia

MYOCARDIAL INFARCTION
Coronary blood flow and myocardial infarction
Manifestations of myocardial infarction
Complications of myocardial infarction
Compensatory mechanisms of myocardial infarction
Treatment of myocardial infarction

HEART FAILURE AND SHOCK
Left heart failure
Right heart failure
Physiologic compensation for heart failure
Diagnosis of congestive heart failure
Treatment of congestive heart failure
Circulatory shock, types.
Stages of shock
Complications of shock
Treatment of shock

ABNORMALITIES OF CARDIAC CONDUCTION
Cardiac conduction system
Cardiac action potential
Electrocardiography
Factors contributing to the development of a cardiac arrhythmia
Mechanisms of cardiac arrhythmia
Types of cardiac arrhythmia
Heart Block
Diagnosis of cardiac arrhythmia
Treatment of cardiac arrhythmia

DISORDERS OF THE RESPIRATORY SYSTEM
Respiratory infections
Obstructive pulmonary disorders
Restrictive pulmonary disorders
Respiratory failure

ABNORMALITIES OF THE KIDNEY AND URINARY TRACT
Functions of the kidney
Renal regulation of blood flow
Evaluation of renal function
Diseases of the kidney
Renal failure
Renal dialysis
Disorders of the bladder and urethra

GASTROINTESTINAL DISORDERS
Symptoms of gastrointestinal disease
Abnormalities of the esophagus
Disorders of the stomach
Disorders of the intestines
Disorders of the gall bladder
Diverticular disease
Colorectal cancer

DISEASE OF THE LIVER AND EXOCRINE PANCREAS
Viral hepatitis
Jaundice
Cirrhosis
Alcoholic Liver Disease
Liver cancer
Disorders of the exocrine pancreas

ENDOCRINE DISORDERS
Hypersecretion of hormones
Hyposecretion of hormones
Altered responsiveness to hormones
Hormones of the hypothalamus
Hormones of the pituitary gland
Disorders of the hypothalamus/anterior pituitary gland
Disorders of the posterior pituitary gland
Alterations in thyroid function
Disorders of the adrenal cortex
Disorders of the adrenal medulla

DIABETES MELLITUS
Hormones of the endocrine pancreas
Type I diabetes mellitus
Type II diabetes mellitus
Treatment of diabetes mellitus
Long term complications of diabetes mellitus
Gestational diabetes
REFERENCES