Description
The new edition of this well-respected text uses a body system approach to studying diseases. This comprehensive textbook, with its traditional presentation of content, integrates basic science with clinical practice and focuses on the alterations in biologic processes that affect the body's equilibrium. Highly readable, it includes shorter, more focused chapters, and end-of-chapter study questions.

Key Features

A body systems approach presents the material in a logical order.
Introductory chapters are included on concepts that affect all body systems to provide a foundation for understanding disease processes.
Anatomy and physiology are reviewed for each body system to provide a basis for understanding the alterations in function affecting that system.
Eighty-two short chapters break content into more manageable sections and make a difficult subject easier to teach and learn.
Outlines with page numbers at the beginning of each chapter help students focus on the most important concepts and provide easy access to chapter content.
Study questions are provided for every chapter to help students review material and assess their knowledge and understanding. Answers are included for immediate feedback.
About 725 illustrations clarify difficult concepts and demonstrate normal and disease processes.
70 full-color plates depict disease manifestations and enhance the text descriptions of these conditions.

Color Plates PART ONE: INTRODUCTION TO GENERAL PATHOLOGY: MECHANISMS OF DISEASE 1. General Concepts of Disease: Health Versus Disease 2. Heredity, Environment, and Disease: Interaction of Heredity and Environment 3. Cellular Injury and Death 4. Response of the Body to Injury: Inflammation and Repair 5. Response of the Body to Immunologic Challenge 6. Response of the Body to Infectious Agents 7. Disturbances in Circulation 8. Disturbances in Growth, Cellular Proliferation, and Differentiation PART TWO: IMMUNE SYSTEM DISORDERS 9. Familiar (IgE-Mediated) Allergic Disorders: Anaphylaxis and the Atopic Diseases 10. Bronchial Asthma: Allergic and Otherwise 11. Atopic Dermatitis and Urticaria 12. Autoimmune and Immune Complex-Induced Diseases 13. Adverse Reactions to Drugs and Related Substances 14. Approaches to Immune Deficiency States 15. Human Immunodeficiency Virus (HIV) and Immunodeficiency Syndrome (AIDS) PART THREE: HEMATOLOGIC SYSTEM DISORDERS 16. The Composition of Blood and the Monocyte-Macrophage System 17. Red Blood Cell Disorders 18. White Blood Cell and Plasma Cell Disorders 19. Coagulation Disorders PART FOUR: FLUID AND ELECTROLYTE DISORDERS 20. Fluid and Electrolyte Balance and Assessment 21. Disorders of Fluid Volume, Osmolality, and Electrolytes 22. Acid-Base Disorders PART FIVE: GASTROINTESTINAL SYSTEM DISORDERS 23. Disorders of the Esophagus 24. Disorders of the Stomach and Duodenum 25. Disorders of the Small Intestine 26. Disorders of the Large Intestine 27. Disorders of the Liver, Gallbladder, and Pancreas PART SIX: CARDIOVASCULAR SYSTEM DISORDERS 28. Anatomy of the Cardiovascular System 29. Physiology of the Cardiovascular System 30. Diagnostic Procedures in Cardiovascular Disease 31. Coronary Atherosclerotic Disease 32. Valvular Heart Disease 33. Cardiac Mechanical Dysfunction and Circulatory Support 34. Vascular Disease PART SEVEN: RESPIRATORY SYSTEM DISORDERS 35. Anatomy and Physiology of the Respiratory System 36. Diagnostic Procedures in Respiratory Disease 37. Cardinal Signs and Symptoms of Respiratory Disease 38. Obstructive Patterns of Respiratory Disease 39. Restrictive Patterns of Respiratory Disease 40. Cardiovascular Disease and the Lung 41. Respiratory Failure 42. Pulmonary Malignant Neoplasms 43. Pulmonary Tuberculosis PART EIGHT: RENAL SYSTEM DISORDERS 44. Anatomy and Physiology of the Kidneys and Urinary Tract 45. Diagnostic Procedures in Renal Disease 46. Chronic Renal Failure 47. End-Stage Renal Disease: Uremic Syndrome 48. Treatment of Chronic Renal Failure 49. Acute Renal Failure PART NINE: NEUROLOGIC SYSTEM DISORDERS 50. Anatomy and Physiology of the Nervous System 51. Evaluation of the Neurologic Patient 52. Pain 53. Cerebrovascular Disease 54. Neurologic Disorders with Generalized Symptomatology 55. Seizure Disorders 56. Central Nervous System Injury 57. Central Nervous System Tumors PART TEN: ENDOCRINE SYSTEM AND METABOLIC DISORDERS 58. Principles of Endocrine and Metabolic Control Mechanisms 59. Disorders of the Pituitary Gland 60. Thyroid Gland Disorders 61. Adrenal Hypersecretion Disorders 62. Adrenal Insufficiency 63. Pancreas: Glucose Metabolism and Diabetes Mellitus PART ELEVEN: REPRODUCTIVE SYSTEM DISORDERS 64. Female Reproductive System Disorders 65. Male Reproductive System Disorders 66. Infections of the Genital Tract PART TWELVE: MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DISORDERS 67. Anatomy and Physiology of Bones and Joints 68. Fractures and Dislocations 69. Tumors of the Musculoskeletal System 70. Osteoarthritis 71. Rheumatoid Arthritis 72. Systemic Lupus Erythematosus 73. Scleroderma 74. Gout 75. Seronegative Spondyloarthropathies PART THIRTEEN: DERMATOLOGIC SYSTEM DISORDERS 76. Anatomy and Physiology of the Skin 77. Acne and Related Conditions 78. Eczema and Vascular Disorders 79. Psoriasis and Pityriasis Rosea 80. Cutaneous Infections 81. Tumors of the Skin 82. Lyme Disease and Infections Answers to Study Questions Index